tissue distribution of artemisinin in broiler chickens following single or multiple oral administration

Tissue distribution of artemisinin in broiler chickens following single or multiple oral administration

Background: Artemisinin is commonly used for the treatment of malaria, but recently has been considered as a potential substance to control poultry coccidiosis. OBJECTIVES: The aim of the present study was to determine the tissue distribution of artemisinin following single or multiple oral administration of different doses in broiler chickens. METHODS: A total number of 390 one day old Ross br...

serum concentration of artemisinin after single and chronic oral dose administration in broiler chickens

although preliminary studies have shown the anticoccidial effects of artemisinin in broiler chickens, there are no proofs of its pharmacokinetics. the objective of this study was to determine the serum concentration of artemisinin after single and multiple oral administration in broiler chickens. a total of 390 one-day-old healthy ross 308 chickens were divided randomly into two groups. in the ...

Pharmacokinetics of ciprofloxacin following intravenous and oral administration in broiler chickens.

Movement and persistence of Salmonella in broiler chickens following oral or intracloacal inoculation.

The dissemination of Salmonella into various lymphoid-like organs in young broiler chicks after oral and intracloacal inoculation was studied. A three-strain cocktail of Salmonella Typhimurium, Salmonella Montevideo, and Salmonella Enteritidis was administered either orally or intracloacally to day-old chicks. After 1 h, 1 day, or 1 week, the ceca, thymus, liver and gallbladder, spleen, and bur...

Pharmacokinetics of Artemisinin in Broiler Chickens after Intravenous and Oral Administrations

Artemisinin (ART), the active ingredient of Artemisia spp. is a promising anticoccidial agent. Since there is no documented information on pharmacokinetics (PK) of this herbal drug in poultry, the present study was carried out to explore PK parameters of ART in broiler chickens. Sixty-four healthy broiler chicks of 21 days old were randomly divided into 4 equal groups. In groups 1 and 2, each b...

The Pharmacokinetics of Rafoxanide following Single Dose Intravenous and Oral Administration in Goats

The study was conducted to determine the plasma concentrations and pharmacokinetic parameters of rafoxanide after a single intravenous (10 mg/kg) and oral (22.5 mg/kg) administrations in black Bengal female goats. Maximum (87.63 11.71 mg/mL) and minimum (1.8 0.24 mg/mL) plasma concentrations of rafoxanide were recorded at 0.08 and 12 h respectively after i.v. administration. The elimination h...